The Buffalo Bills entered the 2022 NFL season with high expectations, but they certainly lived up to the hype in Week 1.

Josh Allen looked very much like an MVP favorite, rolling the Rams in their own building with 353 total yards and four touchdowns. It led to a dominating 31-10 win over the defending Super Bowl champions to put the rest of the league on notice.

But if there’s one team that could make the Bills nervous after that Week 1 performance, it might be the Tennessee Titans.

The Titans have beaten the Bills in the past two NFL seasons, and both times Derrick Henry has absolutely feasted on the Buffalo defense.

MORE: How Derrick Henry owned the Bills during his NFL career

When they last met in Week 6 last season, Henry had 147 yards and 3 touchdowns to lead his team to a 34-31 home win. When the teams met in 2020, he found the end zone twice as the Titans blasted the Bills 42-16.

However, Tennessee heads to Buffalo after a stunning loss to the New York Giants, in which they blew a 13-0 halftime lead. Kicker Randy Bullock also missed a potential winner by 47 yards when time expired.

Sporting News follows live score updates and highlights from Titans vs. Bills on “Monday Night Football”. Follow below for the full NFL Week 2 game results.

AFTER: Watch Titans vs. Bills Live with fuboTV (Free Trial)

Score Titans vs. Bills

Q1 Q2 Q3 Q4 F
Titans seven 0 0 0 0
Invoices seven ten 0 0 0

Titans vs. Bills Live Updates, Monday Night Football Highlights

(all Eastern times)

9:10 p.m. — The Titans defense had a great chance to get off the field, but Allen finds Jamison Crowder 3rd and long to move the chains.

9:06 p.m. — They won’t, however. The Bills defense held on again to force another punt, with a deep ball from Tannehill aimed at Westbrook-Ikhine falling incomplete on 3rd down.

9:03 p.m. — The second half is on with the Titans getting the ball first. They could use some points on this drive to stay within striking distance.

9:01 p.m. — Josh Allen’s first half stats: 18/23, 208 yards, 2 touchdowns and a 133.3 passer rating. Not too bad.

8:58 p.m. — The touchdown was nice, but those celebratory moves from Stefon Diggs might have been even nicer.

8:49 p.m. — A Bills sack on Ryan Tannehill is the last play of the first half. Both offenses started hot, but the Titans calmed down in the second quarter as the Bills held the pedal down to take a two-possession lead.

End of first half: Bills 17, Titans 7

8:46 p.m. — Jackson left the field in an ambulance. Scary scene in Buffalo.

8:41 p.m. — It was a very difficult night in terms of injuries for both teams. Bills corner Dane Jackson is down now, and it looks serious. The cart arrives on the ground to take care of him.

Bills 17, Titans 7

8:36 p.m. TOUCHDOWN — The Bills extend their lead. Josh Allen rushes a left, then spins a right and sends it back across the field to a wide open Stefon Diggs. It’s the star’s second touchdown of the season.

8:34 p.m. — With Buffalo facing another short 4th situation deep in Titans territory, it looks like they’ve been bailed out by an offside call from the defense. However, Sean McDermott called a timeout just before the snap.

8:28 p.m. — Here comes the Bills again. Josh Allen and company have the ball in the red zone thanks to a through ball from Jake Kumerow and a pair of completions to Stefon Diggs. That will take us to the two-minute warning.

8:23 p.m. — For the first time tonight, we have a three-and-out. Buffalo’s defense smothers the Titans to force another punt. On the injury front, Taylor Lewan has been deemed doubtful to return.

Bills 10, Titans 7

8:20 p.m. — Here’s another look at that false start call. The Titans may have taken a break there…

8:17 p.m. — The Bills move downfield again, but a rare misfire from Josh Allen brings the 4th down. After a false start against them, they are forced to take out Tyler Bass, who connects at 49 yards to give Buffalo the lead.

8:07 p.m. — Now the Bills are offering a much-needed stoppage on defense. An offensive face-scoring penalty backs the Titans up, and they can’t convert another long 3rd play. Buffalo has the ball inside its own 20-yard line.

8:02 p.m. — The Titans convert to 3rd and 15th after a nice catch and run from Treylon Burks. They again moved the ball into Bills territory.

End of the first quarter: Bills 7, Titans 7

7:54 p.m. — The Tennessee defense offers a big save. The Bills were driving, but the Titans stuff Josh Allen into the backfield at 4th and run to get the ball back.

Bills 7, Titans 7

7:47 p.m. TOUCHDOWN — The Titans go there in 4th and short from near the goal line, and Derrick Henry fights his way through the middle and into the end zone. It was a HUGE effort on the part of the Titans to respond. What a start to the game.

7:45 p.m. — The Titans have it inside the 5-yard line on a pitch to Nick Westbrook-Ikhine. Buffalo contested the hold, but the game held.

7:40 p.m. — Derrick Henry looks sharp early on, with some great runs to get the Titans offense going again. A throw from Ryan Tannehill to Austin Hooper now puts them in the red zone.

7:37 p.m. — Tennessee’s Trenton Cannon and Buffalo’s Mitch Morse are both doubtful of returning after early injuries. Titans offensive lineman Taylor Lewan also just limped off the field.

Tickets 7, Titans 0

7:30 p.m. TOUCHDOWN — A clinical Bills opener ends with a touchdown. Josh Allen sets up a screen for fullback Reggie Gilliam, who bounces out and finds the corner of the end zone.

7:25 p.m. — Josh Allen hurdles a defender AGAIN. He moves the strings to 3rd and long with outstanding play.

7:23 p.m. — Devin Singletary rips off a big run to bring the Bills attack closer to midfield, but another injury halts the proceedings again. This time it’s Buffalo’s starting center, Mitch Morse, who has to leave the field.

7:17 p.m. — Randy Bullock starts the opening kickoff through the end zone for a touchdown, but already a Titans player is down injured. This is the Trenton Cannon utility.

7:13 p.m. — It’s a great night for football in Western New York. Kick-off is just moments away.

6:57 p.m. — Fun fact: The Titans and Bills have played each other in each of the past five seasons (including tonight). Josh Allen also faced Tennessee in every season of his NFL career. The Titans are looking to pick up three straight wins against their familiar foes tonight.

6:46 p.m. — Looks like you can add Von Miller to the list of people backing Josh Allen to win the MVP award this season.

6:23 p.m. — Stefon Diggs lets loose as he often does while playing wrestling with fans in Buffalo.

6:12 p.m. — The inactive rosters have been released and wide receiver Gabe Davis is OUT for Buffalo with an ankle injury. He is joined by defensive tackle Ed Oliver, who is also out for the Bills. For the Titans, running backs Dontrell Hillard and Julius Chestnut were ruled out along with cornerback Kristian Fulton.

What time is the NFL game tonight?

  • Date: Monday, September 19
  • Time: 7:15 p.m. ET

Titans vs. Bills scheduled to start at 7:15 p.m. ET from Highmark Stadium in Buffalo, NY

What channel is Titans vs. Bills today?

  • TV channel: ESPN
  • Direct: ESPN+, fuboTV (United States) | DAZN (Canada)

Titans vs. Bills will air on ESPN as part of a two-game Monday night special, with Vikings vs. Eagles simulcasting for much of the night on ABC.

ESPN and ABC broadcasts will work to cover both games on both networks, with live looks, score updates and highlights from each game airing on the other channel.

Steve Levy, Louis Riddick and Dan Orlovksy will be on call from Buffalo.